While I'm not affiliated with either product, maybe I can provide a pointer to Steve or Chuck to answer more quickly. Looking at this card, it looks like they're just using some PCI card as a breadboard and there's no connectivity/pins to the motherboard. It gets separately connected to the power on the floppy drive.
See the picture here:
http://www.ufopinball.com/RFM-LED/Ports.htmMy guess is, as long as your new computer has a floppy lead on the power supply it will work, but I'd wait till the experts weigh in

from the "about" the mod page:
Quote:
The actual board was originally designed to mimic an ISA card that fits into the Pinball 2000 Motherboard (this has changed, see below). In actuality, there are no signal lines that run to the motherboard. Power will be supplied to the kit via a floppy drive power connector. I will be including an adapter with the board so that you can tap off the existing power wire bundle, without having to cut any of the existing zip-ties. The phone cords connect to the RFM-LED board through two access holes in the ISA bracket. I will get a better picture of this soon.